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Stage IIIB and Inoperable IIIC
| Treatment Options | STAGE IIIB and Inoperable IIIC tumor of any size with spread to tissues near the breast (skin of the breast or muscles or ribs of the chest wall), and possibly to lymph nodes in the area (IIIB) OR
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| Treatment to the Breast | modified radical mastectomy that may require removal of other nearby tissues involved with the tumor (IIIB); no surgery for inoperable IIIC AND radiation before or after mastectomy |
| Treatment to the Lymph Nodes | axillary lymph node removal by traditional approach AND possible radiation to supraclavicular and/or internal mammary lymph nodes |
| Chemotherapy | chemotherapy almost always recommended |
| Hormonal Therapy | hormonal therapy used for people with hormone-receptor-positive cancer |
| Targeted Therapy | targeted therapy may be used for people with cancers that have certain characteristics (for example, cancers with too many HER2 protein receptors) |
| Treatment to Other Parts of the Body | does not apply |