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Hormonal Therapy Side Effects Comparison Chart

Getting the best breast cancer treatment can feel like a balancing act: you want to do as much as you can to get rid of the cancer and reduce the risk of it coming back. But you'd like to avoid uncomfortable side effects that might lower your quality of life.

When choosing a hormonal therapy medicine, you and your doctor will weigh the benefits and possible side effects of each one. Together, you will decide on a hormonal therapy treatment plan that's right for you and your unique situation.

The table below gives you a summary of some of the most common possible side effects of the different hormonal therapy medicines so you can do a general side-by-side comparison.

For more information on any of these side effects, visit the Treatment Side Effect section.

PDF Version – 120KB

Comparison chart of Hormonal Therapy Side Effects

 ArimidexAromasinFemaraTamoxifenEvistaFarestonFaslodex
bone/joint painyesyesyes yesyes 
osteoporosisyesyesyes    
bone thinningyesyesyes    
nauseayes yesyes yesyes
vomitingyes yes   yes
hot flashesyesyesyesyesyesyesyes
weaknessyesyes     
fatigueyesyesyesyes   
headache yes yes  yes
insomnia yes  yes  
increased sweating    yesyes 
dizziness  yes  yes 
drowsiness  yes    
higher cholesterol  yes    
weight gain  yes    
blood clots   yesyes  
stroke   yesyes  
endometrial cancer   yes yes 
increased bone / tumor pain   yes yes 
mood swings   yes yes 
depression   yes   
hair thinning   yes   
constipation   yes  yes
dry skin   yesyesyes 
loss of libido   yes   
leg cramps    yes  
swelling    yesyes 
flu-like symptoms    yes  
hypercalcemia     yes 
rash     yes 
vaginal discharge / bleeding     yes 
vision problems     yes 
dry eyes     yes 
diarrhea      yes
sore throat      yes
back pain      yes
stomach / abdominal pain      yes
injection site pain      yes

PDF Version – 120KB 

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